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Image Search Results
Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine
Article Title: Effect of zinc intake on hepatic autophagy during acute alcohol intoxication
doi: 10.1007/s10534-018-0077-7
Figure Lengend Snippet: Zinc depletion enhances ethanol induced apoptosis and cell death through inhibition of autophagy. (A) Annexin V levels in VL17-A cells. (B) Representative images of Annexin V and Hoechst staining in VL17A cells. (I) Zinc depleted cells treated with 100 mM ethanol; (II) cells treated with 5 μM and 100 mM ethanol; (III) zinc depleted cells treated with 100 mM ethanol and CQ and (IV) cells treated with 5 μM of zinc, 100 mM ethanol, and CQ. (C) LDH leakage (percentage of “control group” defined as of cells treated with 5 μM zinc (no ethanol or CQ)). Cells were treated as described in figure 5. Some cells were treated with 30 μM of CQ for 6h. Values are average ± SE.*Significantly different (p < 0.05). Annexin V: interaction zinc vs chloroquine p< 0.0001.
Article Snippet: Values were normalized to
Techniques: Inhibition, Staining, Control